By M.J. Elder, W. Bernauer, J.K.G. Dart, F. Bandello
Cicatrizing conjunctivitis is among the such a lot demanding motives of ocular floor affliction at the present time, and with no acceptable intervention, corneal blindness or lack of sight from supervening an infection is usual. simply because a lot of those ailments are infrequent, there's usually constrained administration event on hand and the assets for study into therapy and pathogenesis could be scarce. this article summarizes current remedy techniques and the medical and laboratory experiences validating those techniques. themes mentioned comprise an in-depth examine non-progressive factors together with trachoma, Stevens-Johnson syndrome and ligneous conjunctivitis. The textual content additionally examines power revolutionary conjunctival cicatrization, the illnesses which reason it, their medical and laboratory overview, immunopathogenesis, sequelae and administration. it may reduction the making plans of intervention and therapy of a gaggle of illnesses formerly linked to bad analysis.
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Cicatrizing conjunctivitis is likely one of the such a lot difficult factors of ocular floor sickness this day, and with no acceptable intervention, corneal blindness or lack of sight from supervening an infection is usual. simply because lots of those illnesses are infrequent, there's usually restricted administration event to be had and the assets for learn into therapy and pathogenesis will be scarce.
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Additional info for Cicatrising Conjunctivitis (Developments in Ophthalmology)
Am J Ophthalmol 1989;107:160–166. Rubin BI, Holland EJ, de Smet MD, Belfort R Jr, Nussenblatt RB: Response of reactivated ligneous conjunctivitis to topical cyclosporine (letter). Am J Ophthalmol 1991;112:95–96. Friedlaender MH, Ostler HB: Treatment of ligneous conjunctivitis with cromolyn: A case report. Proctor Bull 1978;1:3. Romain De Cock, FRCS FRCOphth, Consultant Ophthalmologist, Kent & Canterbury NHS Trust, Ethelbert Road, Canterbury CT1 3NG (UK) Membranous, Pseudomembranous and Ligneous Conjunctivitis 45 2 3 Chronic Progressive Conjunctival Cicatrisation 3A The Conditions Bernauer W, Dart JKG, Elder MJ (eds): Cicatrising Conjunctivitis.
Ann Ophthalmol 1985;17:763–765. Holland EJ, Chan C-C, Kuwabara T, Palestine AG, Rowsey JJ, Nussenblatt RB: Immunohistologic findings and results of treatment with cyclosporin in ligneous conjunctivitis. Am J Ophthalmol 1989;107:160–166. Rubin BI, Holland EJ, de Smet MD, Belfort R Jr, Nussenblatt RB: Response of reactivated ligneous conjunctivitis to topical cyclosporine (letter). Am J Ophthalmol 1991;112:95–96. Friedlaender MH, Ostler HB: Treatment of ligneous conjunctivitis with cromolyn: A case report.
A number of conditions involving submucosal fibrosis can produce a clinical picture similar to that seen in the chronic phase of Stevens–Johnson syndrome. These include ocular cicatricial pemphigoid, and various conditions in which chronic inflammation has resulted from infection, as occurs in trachoma, as a result of allergies in several atopic individuals, or damage from chemicals or irradiation. Stevens-Johnson syndrome is usually differentiated from these conditions on the basis of the initial acute illness and perhaps exposure to a known trigger.