Atlas of Alzheimer's Disease by Howard Feldman

By Howard Feldman

Authored through one of many world's top professionals at the administration of Alzheimer's affliction and similar dementias, this hugely illustrated atlas describes the colourful historical past of Alzheimer's affliction; its neuropathological foundation from structural mind imaging and autopsy reports; and its devastating results on notion, cognition, verbal exchange, and social habit. The publication also will position nice emphasis at the more and more identifiable chance elements for improvement of the affliction, with a view in the direction of prevention.

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Early-onset dementia: frequency and causes compared to late-onset dementia. Dement Geriatr Cogn Disord 2006; 21: 59–64. 9. Jellinger K. Prevalence of Alzheimer’s disease in very elderly people: a prospective neuropathological study. Neurology 2002; 58: 671–2; author reply 671–2. 25. Barker WW, Luis CA, Kashuba A et al.

6,16,36,39–42 One source of discrepancy is the rather small numbers in this age group, and a detailed breakdown of this age category is not available in most studies. However, if this finding is indeed true, it would be consistent with the hypothesis that genetic factors predispose a person to develop AD, while other factors modulate the age of onset of clinical dementia. One might hypothesize that those who survive through to this old age and remain cognitively intact have escaped the inheritance of the predisposing genetic risk factors.

14 Incidence of Alzheimer’s disease as a function of age in men and women. (Reprinted with permission from Nussbaum RL, Ellis CE. Alzheimer’s disease and Parkinson’s disease. 58 that the higher prevalence of cerebrovascular disease in men may lead to overdiagnosis of vascular dementia, and consequently an artificial increase in the proportion of women diagnosed with AD. 7 Data extracted from van Duijn et al. Familial aggregation of Alzheimer's disease and related disorders: a collaborative re-analysis of case-control studies.

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