Annual Review of Gerontology and Geriatrics, Volume 19, by David Oslin MD, Paul R. Katz MD, Ira Katz MD PhD, M. Powell

By David Oslin MD, Paul R. Katz MD, Ira Katz MD PhD, M. Powell Lawton PhD

More and more there'll be a requirement from clinicians for a greater knowing of the way to translate learn from easy technology and scientific trials into significant remedy suggestions for overdue lifestyles steel problems. during this quantity the editors have compiled the main state of the art study findings on universal psychological issues within the aged. part 1 addresses methodological concerns and increases serious issues for researchers within the box, reminiscent of how most sensible to layout and enforce huge scientific stories in addition to the way to translate their discovering into perform for psychological wellbeing and fitness services. part II specializes in therapy for particular illnesses equivalent to past due existence melancholy, substance abuse, and psychosis. Of specific be aware are chapters behavioral remedies for folks with Alzheimer's disorder. For clinicians and researchers within the box of gerontology and geriatrics.

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Additional info for Annual Review of Gerontology and Geriatrics, Volume 19, 1999: Focus on Psychopharmacologic Interventions in Late Life

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Confounding effects of medical illness and medication effects; 30 STREIM limitations of self-reporting and floor effects; and the natural course of chronic and progressive illnesses must all be taken into account when measuring outcomes. Great progress has been made in our evolving approaches to measuring outcomes in research on psychopharmacologic interventions in late life. REFERENCES Albert, S. , Del Castillo-Castaneda, C. , Jacobs. D. , & Stern, Y. (1996). Quality of life in patients with Alzheimer's disease as reported by patient proxies.

There is a dire need for pharmacologic studies to employ outcome measures that do a better job of describing the extent and adequacy of treatment response. In fact, most clinical trials currently use assessment instruments that yield dimensional measures of treatment outcome, and can be adapted to achieve these research goals, as discussed in chapter 3. Relevant, measurable outcomes include not only the degree to which individuals experience improvement, but also the proportion of patients who improve to a sufficient degree, and the proportion who have sustained remission over specified follow-up periods.

Various instruments have been used to measure psychiatric and behavioral symptoms in Alzheimer patients, and some investigators have recently employed these as primary outcome measures (Cummings, 1997). Some investigators have explored the use of Goal Attainment Scaling (GAS) to measure treatment effects (Rockwood, Stolee, Howard, & Mallery, 1996). This employs an individualized approach to setting goals in areas of self-care, behavior, cognition, and leisure activities; and then measuring attainment of individual goals to determine treatment benefit.

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