By Chamberlain JS
Read or Download A textbook of organic chemistry PDF
Best organic chemistry books
Methoden der Organischen Chemie (Methods of natural Chemistry, known as Houben-Weyl) is a typical reference paintings for chemists engaged in natural synthesis. In volumes on compound periods, together with all Supplemental volumes, preparative tools are taken care of comprehensively and significantly. Tables of examples evaluate an important tools and convey their scope.
Solid-phase synthesis of carbohydrates provides designated demanding situations to artificial chemists and at the moment represents one of many most popular parts of analysis in bioorganic chemistry. reliable aid Oligosaccharide Synthesis and Combinatorial Carbohydrate Libraries addresses the intriguing expectation that solid-phase meeting of oligosaccharides could have a basic effect at the box of glycobiology.
This moment version comprises consise details on 134 rigorously selected named natural reactions - the normal set of undergraduate and graduate artificial natural chemistry classes. every one response is certain with basically drawn mechanisms, references from the first literature, and well-written money owed overlaying the mechanical features of the reactions, and the main points of facet reactions and substrate barriers.
- Elements of organic photochemistry
- Organic reaction mechanisms 1998..An annual survey
- Laboratory Experiments For General, Organic and Biochemistry
- General, Organic, and Biological Chemistry (5th Edition)
- Solvent-Free Organic Synthesis
Extra resources for A textbook of organic chemistry
45 Disaccharide 66 was extended in standard fashion to trisaccharide 67 and fully protected to give 68. This latter compound was treated with anthracenesulfonamide and I(sym-coll)2ClO4 to form the intermediate 69. Reaction of the iodosulfonamide 69 with tetra-n-butylammonium azide followed by acetylation provided the anomeric azide 70. The anthracenesulfonamide linkage was cleaved under mild, solid support compatible conditions such as thiophenol or 1,3-propanedithiol and Hünigs base. 3 Complex-type biantennary structure.
22 Synthesis of N-linked glycopeptides on a solid support. 23 Solid-phase synthesis of glycopeptides. give glycopeptide 86. Retrieval from the solid support afforded trisaccharide octapeptide 87 in 18% overall yield from 10. The methodology described above has proved to be effective for other glycosylation sequences. 23 shows conversion of a variety of disaccharides to their respective glycopeptides. For example, lactal derivative 31 was transformed into a lactosamine-linked glycopeptide where C6 of the glucosamine residue is protected as its benzyl ether, in 24% overall yield.
Chem. , and Garegg, P. , Carbohydr. Res. 149, C9C12 (1986). , Liebigs Ann. Chem. 4148 (1982). , Liebigs Ann. Chem. 717730 (1986). , Seeberger, P. , and Danishefsky, S. , J. Org. Chem. 63, 11261130 (1998). (a) Griffith, D. , and Danishefsky, S. , J. Am. Chem. Soc. , Nishida, A. , J. Am. Chem. Soc. 108, 140145 (1986). , Seeberger, P. , and Danishefsky, S. , Angew. , Int. Ed. 37, 786789 (1998). , Roth, K. , Science 262, 18921895 (1993). 40 THE GLYCAL ASSEMBLY METHOD ON SOLID SUPPORTS 27. , Science 260, 159160 (1993).